Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094768 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1HPGDGABRA2GABRB2 | |
| SCHEMBL11070583 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1HPGDGABRA2GABRB2 | |
| SCHEMBL3498584 | 0.88 | KDM4E (0.49) | PPARGKDM4EALDH1A1HPGDGABRA2 | |
| SCHEMBL8193595 | 0.85 | GABRA2 (0.47) | KDM4EALDH1A1HPGDGABRA2GABRB2 | |
| SCHEMBL1202722 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1HPGDGABRA2GABRB2 | |
| SCHEMBL11094584 | 0.84 | PPARG (0.57) | PPARGKDM4EALDH1A1HPGDGABRA2 | |
| SCHEMBL7849956 | 0.81 | PPARG (0.60) | PPARGKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL7274580 | 0.81 | PSEN1 (0.57) | KDM4EALDH1A1HPGDGABRA2GABRB2 | |
| SCHEMBL8564199 | 0.80 | MAPT (0.51) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11099677 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0033094-A1 | Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |