Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340226 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11582004 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11582898 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11867146 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11582889 | 0.81 | LMNA (0.77) | MAPK1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL11582947 | 0.81 | LMNA (0.51) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11859664 | 0.80 | CSNK1D (0.53) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11348393 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPK1TDP1LMNA | |
| SCHEMBL11583270 | 0.79 | LMNA (0.64) | MAPK1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL11582935 | 0.79 | LMNA (0.64) | MAPK1LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031120-B1 | A PROCESS FOR THE PRODUCTION OF 2-SUBSTITUTED 6-ALKOXYCARBONYL-8-ETHYL-5-OXO-5,8-DIHYDRO-PYRIDO(2,3-D)-PYRIMIDINES AND OF CORRESPONDING FREE ACIDS | Unibios S.p.A. (IT) | 1984-08-01 | — | — | EP | claimed |
| EP-0031120-B1 | A PROCESS FOR THE PRODUCTION OF 2-SUBSTITUTED 6-ALKOXYCARBONYL-8-ETHYL-5-OXO-5,8-DIHYDRO-PYRIDO(2,3-D)-PYRIMIDINES AND OF CORRESPONDING FREE ACIDS | Unibios S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |
| EP-0031120-A1 | A process for the production of 2-substituted 6-alkoxycarbonyl-8-ethyl-5-oxo-5,8-dihydro-pyrido(2,3-d)-pyrimidines and of corresponding free acids | Unibios S.p.A. (IT) | 1981-07-01 | — | — | EP | disclosed |