Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339697 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL5094504 | 0.85 | LMNA (0.58) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL11098552 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL3318354 | 0.79 | LMNA (0.53) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL3977245 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL3704116 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL11289462 | 0.78 | POLB (0.53) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL11789908 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL3696586 | 0.78 | LMNA (0.64) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL5468538 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008610-B1 | FURONAPHTHYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-10-14 | — | — | EP | disclosed |
| US-4293695-A | ANTIBACTERIAL AGENTS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| EP-0008610-A1 | Furonaphthyridine compounds, process for their preparation and pharmaceutical compositions containing them | DAIICHI SEIYAKU CO., LTD. (JP) | 1980-03-19 | — | — | EP | disclosed |