Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582200 | 0.87 | BAZ2B (0.49) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL11098552 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL11340226 | 0.85 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL11582898 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL8703572 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL10987423 | 0.82 | ADRB2 (0.42) | ALDH1A1SMN1; SMN2POLBMAPTTDP1 | |
| SCHEMBL11867146 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL11582889 | 0.81 | LMNA (0.77) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL11582947 | 0.81 | LMNA (0.51) | ALDH1A1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL11859664 | 0.80 | CSNK1D (0.53) | ALDH1A1SMN1; SMN2POLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129737-A | Process for the preparation of an 8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acid | LABORATOIRE ROGER BELLON (FR) | 1978-12-12 | — | — | US | disclosed |
| US-4034094-A | 8-Alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acids for treating urinary tract infections | LABORATOIRE ROGER BELLOW (FR) | 1977-07-05 | — | — | US | disclosed |
| US-3962443-A | Antibacterial pharmaceutical compositions and processes for preparation thereof | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-06-08 | — | — | US | disclosed |
| US-3950338-A | BACTERICIDES | LABORATOIRE ROGER BELLON (FR) | 1976-04-13 | — | — | US | disclosed |