Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352938 | 0.84 | KDM4E (0.48) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL11366969 | 0.83 | NPC1 (0.48) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL11358780 | 0.82 | RAB9A (0.60) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL11099409 | 0.77 | KMT2A (0.48) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL11544400 | 0.75 | MEN1 (0.68) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL11107427 | 0.75 | RAB9A (0.55) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL11108273 | 0.75 | RAB9A (0.60) | RAB9ANPC1KMT2APOLBKDM4E | |
| SCHEMBL1321188 | 0.74 | MAOA (0.59) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL11106960 | 0.74 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL11356167 | 0.74 | TBK1 (0.52) | RAB9ANPC1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |