SCHEMBL11099741

SCHEMBL11099741

C=CC=Cc1ccc(C=C)cc1C=Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP1B1 Q16678 1/20 0.41
NFE2L2 Q16236 4/20 0.39
TRPA1 O75762 3/20 0.39
RELA Q04206 2/20 0.38
MAOB P27338 3/20 0.38
CYP19A1 P11511 2/20 0.37
MAOA P21397 2/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78055 0.86 ALDH1A1 (0.48) ALDH1A1TSHRCYP1A1CYP1A2CYP1B1
SCHEMBL27453293 0.82 ALDH1A1 (0.40) ALDH1A1TSHRTRPA1TP53TDP1
SCHEMBL11547658 0.80 RELA (0.56) CYP1A1CYP1A2CYP1B1NFE2L2TRPA1
SCHEMBL11547663 0.80 RELA (0.56) CYP1A1CYP1A2CYP1B1NFE2L2TRPA1
SCHEMBL28195017 0.78 MAOB (0.62) ALDH1A1TSHRNFE2L2TRPA1RELA
SCHEMBL9246477 0.76 MAOB (0.61) ALDH1A1TSHRNFE2L2TRPA1MAOB
Styrene SCHEMBL10784465 0.76 ALDH1A1 (0.67) ALDH1A1TSHRCYP1A2NFE2L2TRPA1
Styrene SCHEMBL10534525 0.76 ALDH1A1 (0.67) ALDH1A1TSHRCYP1A2NFE2L2TRPA1
Styrene SCHEMBL10493198 0.76 ALDH1A1 (0.67) ALDH1A1TSHRCYP1A2NFE2L2TRPA1
SCHEMBL11289680 0.75 ALOX5 (0.42) ALDH1A1CYP1A1CYP1A2CYP1B1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4480057-A WITH CRYSTALLINE OLEFIN POLYMER, OR HYDROGENATED STYRENE-CONJUGATED DIENE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1984-10-30 US disclosed