Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100690 | 0.89 | TDP1 (0.58) | PRKCZKDM4ERAB9APIN1TDP1 | |
| SCHEMBL11101188 | 0.87 | PIN1 (0.49) | PRKCZKDM4ERAB9APIN1KMO | |
| SCHEMBL17771956 | 0.85 | KDM4E (0.51) | KDM4EPIN1TDP1CYP3A4CYP2C9 | |
| SCHEMBL11097630 | 0.84 | PIN1 (0.45) | RAB9APIN1TDP1CYP1A2CYP3A4 | |
| SCHEMBL11104899 | 0.84 | MAPT (0.44) | KDM4ERAB9APIN1CYP3A4 | |
| SCHEMBL5294080 | 0.83 | PRKAG1 (0.59) | PRKCZ | |
| SCHEMBL11100700 | 0.83 | PRKAG1 (0.59) | PRKCZ | |
| SCHEMBL2301507 | 0.82 | PRKCZ (0.50) | PRKCZKDM4ERAB9APIN1TDP1 | |
| Hydrochloric Acid SCHEMBL657786 | 0.81 | PRKCZ (0.49) | PRKCZKDM4ERAB9APIN1TDP1 | |
| SCHEMBL13957601 | 0.81 | ALDH1A1 (0.48) | KDM4ERAB9APIN1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042753-B1 | NONAPEPTIDE AND DECAPEPTIDE AGONISTS OF LUTEINIZING HORMONE RELEASING HORMONE CONTAINING HETEROCYCLIC AMINO ACID RESIDUES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM, AND THEIR PHARMACEUTICAL USE | SYNTEX (U.S.A.) INC. (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4318905-A | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues | SYNTEX (U.S.A.) INC. (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |