Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109253 | 0.88 | ALDH1A1 (0.45) | DRD2ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL11101849 | 0.85 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL11102550 | 0.81 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL11111799 | 0.81 | PDE5A (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11110639 | 0.79 | DRD2 (0.43) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL11110238 | 0.79 | LMNA (0.45) | ALDH1A1KDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11101546 | 0.76 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL11110872 | 0.75 | LMNA (0.50) | ALDH1A1KDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11105028 | 0.75 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL11255217 | 0.75 | LDHA (0.63) | ALDH1A1KDM4EHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |