Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.36 |
| ▸ | MMP9 | P14780 | 8/20 | 0.36 |
| ▸ | MMP12 | P39900 | 8/20 | 0.36 |
| ▸ | MMP13 | P45452 | 7/20 | 0.36 |
| ▸ | MMP8 | P22894 | 6/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110145 | 0.90 | KDM4E (0.41) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL1110342 | 0.89 | MMP2 (0.34) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL1110250 | 0.89 | MMP12 (0.38) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL1110220 | 0.87 | NPC1 (0.42) | BCHEACHEPPARGPPARDPPARA | |
| SCHEMBL1110207 | 0.87 | ALDH1A1 (0.45) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL1321251 | 0.87 | MMP12 (0.36) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL1110337 | 0.87 | FFAR1 (0.40) | BRD4 | |
| SCHEMBL1110210 | 0.87 | MAPK14 (0.38) | TP53MAPTPPARGPPARDPPARA | |
| SCHEMBL1110203 | 0.86 | ACLY (0.32) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL1110163 | 0.86 | PPARG (0.41) | MAPTPPARGPPARDPPARAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269761-A1 | ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| EP-2279173-A1 | NEW ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269761-A1 | ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | SULT2A1, UGT1A1, SLC5A1 | MMP2 3127/4885MMP9 3948/4885MMP12 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.