SCHEMBL11107668

SCHEMBL11107668

Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2cc(Cl)ccc2OC(F)(F)C(F)F)n1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALPL P05186 4/20 0.43
LMNA P02545 1/20 0.41
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.38
PCTP Q9UKL6 2/20 0.38
STARD7 Q9NQZ5 1/20 0.38
STARD10 Q9Y365 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11110826 0.93 ALPL (0.41) ALPLLMNATSHRALDH1A1GAA
SCHEMBL11003560 0.91 ALPL (0.52) ALPLLMNATSHRALDH1A1GAA
SCHEMBL11004041 0.87 TSHR (0.46) LMNATSHRALDH1A1GAA
SCHEMBL11115191 0.82 ALOX15 (0.45) ALPLTSHRALDH1A1GAAKMT2A
SCHEMBL11108466 0.82 PCTP (0.43) TSHRALDH1A1GAAPCTPSTARD7
SCHEMBL11115042 0.82 ALDH1A1 (0.43) LMNATSHRALDH1A1GAA
SCHEMBL11112567 0.81 LMNA (0.40) LMNATSHRALDH1A1GAAKMT2A
SCHEMBL10999615 0.80 GAA (0.51) TSHRALDH1A1GAA
SCHEMBL11116171 0.80 ALPL (0.48) ALPLLMNATSHRKMT2APCTP
SCHEMBL3599016 0.79 TSHR (0.42) LMNATSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023422-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP claimed