SCHEMBL111108

SCHEMBL111108

CCC(N)(CC)c1cc(N)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.46
PDE10A Q9Y233 1/20 0.45
ACHE P22303 2/20 0.44
CASP1 P29466 2/20 0.41
TSHR P16473 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ESR1 P03372 5/20 0.39
ESR2 Q92731 3/20 0.39
AR P10275 2/20 0.39
ALOX15 P16050 3/20 0.37
HSD17B10 Q99714 3/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP2C9 P11712 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
TNF P01375 1/20 0.37
CYP3A4 P08684 1/20 0.37
HSPD1 P10809 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6256851 0.98 ACHE (0.47) PRKCIPDE10AACHECASP1TSHR
SCHEMBL1498026 0.83 PRKCI (0.44) PRKCIPDE10AACHECASP1TSHR
SCHEMBL22683203 0.83 PRKCI (0.44) PRKCIPDE10AACHECASP1TSHR
SCHEMBL7153227 0.83 PRKCI (0.44) PRKCIPDE10AACHECASP1TSHR
SCHEMBL11518066 0.81 PRKCI (0.46) PRKCIPDE10AACHECASP1TSHR
SCHEMBL11269727 0.81 ESR1 (0.46) ESR1ESR2ARALOX15HSD17B10
SCHEMBL4639799 0.79 PRKCI (0.44) PRKCIPDE10AACHECASP1TSHR
SCHEMBL9193361 0.79 CA1 (0.39) PRKCIPDE10AACHECASP1TSHR
SCHEMBL7035205 0.79 ALDH1A1 (0.38) PRKCIESR1ESR2ARALOX15
SCHEMBL5619681 0.79 ESR1 (0.36) PRKCIESR1ESR2ARALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
WO-2021018445-A1 OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR HENKEL AG & CO. KGAA (DE) 2021-02-04 WO claimed
EP-3082751-B1 TETRASUBSTITUTED PYRIMIDINE DERIVATIVES IN OXIDATIVE DYEING PREPARATIONS HENKEL AG & CO KGAA (DE) 2018-09-19 EP claimed
US-9636288-B2 Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine HENKEL AG & CO. KGAA (DE) 2017-05-02 US claimed
EP-3082751-A1 MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE Henkel AG & Co. KGaA (DE) 2016-10-26 EP claimed
US-20160296447-A1 MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE HENKEL AG & CO. KGAA (DE) 2016-10-13 US claimed
WO-2015090292-A1 MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE HENKEL AG & CO. KGAA (DE) 2015-06-25 WO claimed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN claimed
WO-2005051336-A1 METHOD FOR DYEING FIBRES CONTAINING KERATINE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-09 WO claimed
US-6852133-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-02-08 US claimed
US-20040139564-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-07-22 US claimed
EP-1438948-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-07-21 EP claimed
EP-1434560-A1 METHOD FOR DYEING AND SUBSEQUENT BLEACHING OF HAIR Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
WO-2003030849-A1 METHOD FOR DYEING AND SUBSEQUENT BLEACHING OF HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1239817-A1 USE OF METHYLCHINOLINIUM COMPOUNDS FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-18 EP claimed
WO-2001047483-A1 USE OF METHYLCHINOLINIUM COMPOUNDS FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO claimed
EP-0857477-B1 Hair dye GOLDWELL GMBH (DE) 1999-07-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160296447-A1 MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE KRT18, TK1, DPYD PRKCI 1369/4885PDE10A 4784/4885ACHE 2756/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO PRKCI 3109/4885PDE10A 1214/4885ACHE 858/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO PRKCI 3109/4885PDE10A 1214/4885ACHE 858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.