Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153227 | 1.00 | PRKCI (0.44) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL22683203 | 1.00 | PRKCI (0.44) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL111108 | 0.83 | PRKCI (0.46) | PRKCIPDE10AACHECASP1TSHR | |
| Hydrochloric Acid SCHEMBL6256851 | 0.81 | ACHE (0.47) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL11518066 | 0.79 | PRKCI (0.46) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL4639799 | 0.78 | PRKCI (0.44) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL3338261 | 0.76 | PDE10A (0.50) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL8440155 | 0.76 | PDE10A (0.50) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL17774733 | 0.76 | PDE10A (0.45) | PRKCIPDE10AACHECASP1TSHR | |
| SCHEMBL17774737 | 0.76 | PDE10A (0.45) | PRKCIPDE10AACHECASP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638321-B1 | Oxidation color dyes for hair from aniline compounds | L'OREAL (FR) | 2003-10-28 | — | — | US | claimed |
| US-6602303-B2 | And a combination of an alkoxylated or glycerolated fatty alcohol and a hydroxylated | L'OREAL S.A. (FR) | 2003-08-05 | — | — | US | claimed |
| US-6565614-B1 | Mixture containing quaternary ammonium compound | L'OREAL (FR) | 2003-05-20 | — | — | US | claimed |
| US-6537328-B1 | Hair dye | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| US-20030000026-A9 | Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods | L'OREAL S.A. (FR) | 2003-01-02 | — | — | US | claimed |
| US-20020046431-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods | LAURENT FLORENCE (FR) | 2002-04-25 | — | — | US | claimed |
| EP-4362889-A1 | COMPOSITION COMPRISING AT LEAST ONE OXIDATION DYE, 1,3-PROPANEDIOL, AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE FATTY SUBSTANCE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362902-A1 | COMPOSITIONS CONTAINING DIRECT DYES FOR IMPARTING COLOR AND TONE TO THE HAIR | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362891-A1 | COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362906-A1 | COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023105016-A1 | COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS AND A PHOSPHORIC SURFACTANT | L'OREAL (FR) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023105021-A1 | COMPOSITION COMPRISING A PARTICULAR OXIDATION DYE PRECURSOR AND A PARTICULAR AMINO SILICONE | L'OREAL (FR) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023105015-A1 | COMPOSITION COMPRISING A PARTICULAR OXIDATION DYE PRECURSOR, AN OXYALKYLENATED FATTY ALCOHOL AND A POLYSACCHARIDE | L'OREAL (FR) | 2023-06-15 | — | — | WO | disclosed |
| US-20060005324-A1 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
| US-20050188478-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one sugar-based nonionic surfactant, and a process using this composition | L'OREAL S.A. (FR) | 2005-09-01 | — | — | US | disclosed |
| US-6692539-B2 | Cationic or amphoteric polymer whose cationic charge density is greater than or equal to 2 meq/gram. | L'OREAL (FR) | 2004-02-17 | — | — | US | disclosed |
| US-20030229948-A1 | Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated caboxylic acid ether, a mono-or polyglycerolated surfactant and a nonionic oxyalkylenated surfactant | L'OREAL (FR) | 2003-12-18 | — | — | US | disclosed |
| US-20030192134-A1 | Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol | L'OREAL (FR) | 2003-10-16 | — | — | US | disclosed |
| US-20030172473-A1 | Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer | L'OREAL (FR) | 2003-09-18 | — | — | US | disclosed |
| US-20030172475-A1 | Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono-or polyglycerolated surfactant and an unsaturated fatty alcohol | L'OREAL (FR) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030000026-A9 | Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods | KRT18, ACAD10, OAT | PRKCI 743/4885PDE10A 3292/4885ACHE 3689/4885 |
| US-20030192134-A1 | Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol | KRT18, ELOVL5, FASN | PRKCI 384/4885PDE10A 3924/4885ACHE 4166/4885 |
| US-20060005324-A1 | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | KRT18, DSC1, DSG1 | PRKCI 889/4885PDE10A 4178/4885ACHE 1242/4885 |
| US-20030172473-A1 | Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer | KRT18, KRTCAP2, CUTA | PRKCI 220/4885PDE10A 4418/4885ACHE 3390/4885 |
| US-20030172475-A1 | Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono-or polyglycerolated surfactant and an unsaturated fatty alcohol | KRT18, HACD3, ELOVL5 | PRKCI 319/4885PDE10A 3999/4885ACHE 4349/4885 |
| US-20050188478-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one sugar-based nonionic surfactant, and a process using this composition | KRT18, SORD, HKDC1 | PRKCI 1300/4885PDE10A 4144/4885ACHE 182/4885 |
| US-20030229948-A1 | Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated caboxylic acid ether, a mono-or polyglycerolated surfactant and a nonionic oxyalkylenated surfactant | KRT18, KRTCAP2, PLOD2 | PRKCI 396/4885PDE10A 3836/4885ACHE 4235/4885 |
| US-20020046431-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods | KRT18, ACAD10, OAT | PRKCI 743/4885PDE10A 3292/4885ACHE 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.