Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 6/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981659 | 0.83 | RYR2 (0.38) | RYR2SIGMAR1 | |
| SCHEMBL10967062 | 0.79 | RYR2 (0.36) | RYR2HSD17B3 | |
| SCHEMBL16095582 | 0.71 | SDCBP (0.40) | RYR2HSD17B3 | |
| SCHEMBL17185647 | 0.71 | RYR2 (0.36) | RYR2SIGMAR1HSD17B3MAOAMAOB | |
| SCHEMBL19674181 | 0.71 | RYR2 (0.40) | RYR2SIGMAR1HSD17B3MAOAMAOB | |
| SCHEMBL31146716 | 0.71 | RYR2 (0.36) | RYR2SIGMAR1HSD17B3MAOAMAOB | |
| SCHEMBL6969929 | 0.71 | RYR2 (0.40) | RYR2SIGMAR1HSD17B3MAOAMAOB | |
| SCHEMBL11118465 | 0.71 | RYR2 (0.40) | RYR2SIGMAR1HSD17B3MAOAMAOB | |
| SCHEMBL3894929 | 0.71 | RYR2 (0.36) | RYR2SIGMAR1HSD17B3MAOAMAOB | |
| SCHEMBL11217635 | 0.71 | MAOA (0.40) | RYR2SIGMAR1HSD17B3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029940-B1 | PROCESS FOR THE PREPARATION OF 2,2'-IMINO-BIS BENZOTHIAZOLE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0029940-A1 | Process for the preparation of 2,2'-imino-bis benzothiazole compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-10 | — | — | EP | disclosed |