Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111087 | 0.83 | RYR2 (0.37) | RYR2SIGMAR1 | |
| SCHEMBL10967062 | 0.76 | RYR2 (0.36) | RYR2 | |
| SCHEMBL6185179 | 0.72 | RYR2 (0.36) | RYR2SIGMAR1 | |
| SCHEMBL16095582 | 0.69 | SDCBP (0.40) | RYR2 | |
| SCHEMBL17185647 | 0.68 | RYR2 (0.36) | RYR2SIGMAR1 | |
| SCHEMBL3894929 | 0.68 | RYR2 (0.36) | RYR2SIGMAR1 | |
| SCHEMBL11118465 | 0.68 | RYR2 (0.40) | RYR2SIGMAR1 | |
| SCHEMBL19674181 | 0.68 | RYR2 (0.40) | RYR2SIGMAR1 | |
| SCHEMBL6969929 | 0.68 | RYR2 (0.40) | RYR2SIGMAR1 | |
| SCHEMBL11217635 | 0.68 | MAOA (0.40) | RYR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286987-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung (AT) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094340-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | INNOVATIONSAGENTUR GESELLSCHAFT M.B.H. (AT) | 2001-12-13 | — | — | WO | disclosed |