Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113224 | 0.93 | TBXAS1 (0.40) | ALDH1A1ALOX15TBXAS1SMPD1HTR2C | |
| SCHEMBL11115014 | 0.90 | TBXAS1 (0.40) | TBXAS1SMPD1BCHEACHEHTR2C | |
| SCHEMBL11111420 | 0.88 | ALOX15 (0.40) | ALDH1A1ALOX15TBXAS1SMPD1BCHE | |
| SCHEMBL11119745 | 0.87 | ALDH1A1 (0.39) | ALDH1A1ALOX15TBXAS1SMPD1BCHE | |
| SCHEMBL11114001 | 0.87 | MEN1 (0.40) | ALDH1A1ALOX15TBXAS1SMPD1BCHE | |
| SCHEMBL11116048 | 0.85 | TBXAS1 (0.41) | ALDH1A1TBXAS1SMPD1HTR2CHTR2A | |
| SCHEMBL11112434 | 0.85 | SMPD1 (0.45) | ALDH1A1ALOX15TBXAS1SMPD1HTR2A | |
| SCHEMBL10999576 | 0.83 | TBXAS1 (0.46) | ALDH1A1ALOX15TBXAS1HTR2CSLC6A3 | |
| SCHEMBL11114115 | 0.81 | TBXAS1 (0.39) | ALDH1A1ALOX15TBXAS1HTR2CHTR2A | |
| SCHEMBL11129673 | 0.80 | TBXAS1 (0.38) | ALDH1A1ALOX15TBXAS1HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |
| EP-0038564-A1 | Dibenz (b,e) oxepin derivatives and pharmaceutical compositions comprising them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1981-10-28 | — | — | EP | disclosed |