Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116115 | 1.00 | TRPA1 (0.40) | TRPA1TGM2MEN1KMT2AKDM4E | |
| SCHEMBL29454416 | 0.84 | MEN1 (0.42) | TRPA1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL677773 | 0.84 | MEN1 (0.42) | TRPA1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11115877 | 0.78 | S100A4 (0.38) | TGM2ALDH1A1NPSR1TP53IDO1 | |
| SCHEMBL11115874 | 0.78 | S100A4 (0.38) | TGM2ALDH1A1NPSR1TP53IDO1 | |
| SCHEMBL11115938 | 0.78 | HSD17B3 (0.38) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11115316 | 0.78 | HSD17B3 (0.38) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11118131 | 0.78 | S100A4 (0.38) | TGM2ALDH1A1NPSR1TP53IDO1 | |
| SCHEMBL11113798 | 0.72 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL11114767 | 0.72 | TRPA1 (0.46) | TRPA1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |