Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SOD1 | P00441 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112404 | 0.83 | PIK3CD (0.53) | L3MBTL1PIK3CDPIK3R1DRD2DRD4 | |
| SCHEMBL11101849 | 0.73 | DRD2 (0.47) | LMNAHTTKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11106942 | 0.73 | ALDH1A1 (0.47) | LMNAHTTPIK3CDPIK3R1KMT2A | |
| SCHEMBL11109561 | 0.72 | DRD2 (0.47) | POLBPIK3CDPIK3R1DRD2DRD4 | |
| SCHEMBL16217340 | 0.72 | HTR1B (0.58) | LMNAHTTPOLBL3MBTL1KMT2A | |
| SCHEMBL11110243 | 0.71 | PIK3CD (0.39) | LMNAHTTPOLBPIK3CDPIK3R1 | |
| SCHEMBL11105878 | 0.71 | HTR1B (0.41) | LMNAPIK3CDPIK3R1KMT2ASMN1; SMN2 | |
| SCHEMBL18591808 | 0.70 | POLB (0.52) | LMNAHTTPOLBL3MBTL1KMT2A | |
| SCHEMBL11110238 | 0.70 | LMNA (0.45) | LMNAHTTPOLBL3MBTL1PIK3CD | |
| SCHEMBL11105916 | 0.70 | S1PR4 (0.47) | LMNAHTTL3MBTL1PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |