Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102648 | 0.78 | DRD2 (0.37) | MAOAMAOBOPRD1DRD2CHRM3 | |
| SCHEMBL8974576 | 0.76 | CA2 (0.34) | — | |
| SCHEMBL11112582 | 0.76 | SLC6A2 (0.37) | DRD2CHRM3DRD3 | |
| SCHEMBL11113792 | 0.76 | PARP1 (0.34) | MAOAMAOBPARP1 | |
| SCHEMBL5544997 | 0.74 | MAOA (0.62) | MAOAMAOBOPRD1DRD2CHRM3 | |
| SCHEMBL7079080 | 0.71 | MAOA (0.46) | MAOAMAOBDRD2CHRM3PARP1 | |
| SCHEMBL11113788 | 0.70 | LMNA (0.54) | CHRM3PARP1 | |
| SCHEMBL9904926 | 0.70 | MAOA (0.41) | MAOAMAOBDRD2CHRM3 | |
| SCHEMBL6465805 | 0.70 | — | — | |
| SCHEMBL17818432 | 0.69 | CHRNB4 (0.41) | MAOAMAOBOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103173-A1 | Carbamic-acid esters, process and starting material for their preparation, parasiticides containing these esters as active products, as well as the use of such esters and agents in combating parasites | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-03-21 | — | — | EP | disclosed |