Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113243 | 0.83 | KDM4E (0.33) | RXRARXRBRXRGSLC6A3 | |
| SCHEMBL11485763 | 0.80 | PARP1 (0.55) | PARP1RXRARXRBRXRGMAOA | |
| SCHEMBL11113014 | 0.76 | MAOA (0.42) | PARP1MAOAMAOB | |
| SCHEMBL11114385 | 0.74 | CXCR5 (0.36) | PARP1RXRARXRBRXRG | |
| SCHEMBL11109588 | 0.73 | BRD4 (0.32) | — | |
| SCHEMBL10801507 | 0.72 | GAA (0.33) | RXRARXRBRXRGMAOB | |
| SCHEMBL11109609 | 0.69 | ALDH1A1 (0.33) | RXRARXRBRXRG | |
| SCHEMBL10801217 | 0.69 | RXRA (0.32) | RXRARXRBRXRG | |
| SCHEMBL946263 | 0.69 | LMNA (0.49) | — | |
| SCHEMBL11110558 | 0.69 | ALDH1A1 (0.35) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103173-A1 | Carbamic-acid esters, process and starting material for their preparation, parasiticides containing these esters as active products, as well as the use of such esters and agents in combating parasites | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-03-21 | — | — | EP | claimed |
| EP-0103173-A1 | Carbamic-acid esters, process and starting material for their preparation, parasiticides containing these esters as active products, as well as the use of such esters and agents in combating parasites | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-03-21 | — | — | EP | disclosed |