Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | HTT | P42858 | 6/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837849 | 0.79 | LMNA (0.55) | LMNAHTTNPSR1SMN1; SMN2KMT2A | |
| SCHEMBL27977126 | 0.79 | ALDH1A1 (0.45) | LMNAHTTNPSR1SMN1; SMN2GAA | |
| SCHEMBL8612119 | 0.78 | LTA4H (0.53) | LMNAHTTNPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL5873436 | 0.76 | HTT (0.53) | LMNAHTTNPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL20228977 | 0.75 | MAOB (0.51) | SIGMAR1MAOBCYP1A2CHRM3IDO1 | |
| SCHEMBL10368035 | 0.75 | HTT (0.56) | LMNAHTTNPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL27698267 | 0.74 | CYP1A2 (0.51) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4747589 | 0.73 | HTT (0.53) | LMNAHTTNPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL8325279 | 0.73 | TAAR1 (0.53) | SIGMAR1MAOBCYP1A2CHRM3IDO1 | |
| SCHEMBL30183964 | 0.73 | TAAR1 (0.53) | SIGMAR1MAOBCYP1A2CHRM3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273070-B2 | Organozinc complexes and processes for making and using the same | KNOCHEL PAUL (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9273070-B2 | Organozinc complexes and processes for making and using the same | KNOCHEL PAUL (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) | 2014-01-30 | — | — | US | disclosed |
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) | 2014-01-30 | — | — | US | disclosed |
| WO-2012085168-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | ODC1, AOC1, ADH1C | LMNA 3145/4885HTT 3830/4885NPSR1 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.