SCHEMBL11113544

SCHEMBL11113544

CCCCOC(=O)Cc1ccc(C(N)S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 1/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
MMP1 P03956 3/20 0.39
MMP7 P09237 3/20 0.39
MMP12 P39900 3/20 0.39
MMP13 P45452 3/20 0.39
ACE P12821 2/20 0.39
HSD17B10 Q99714 2/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20981391 0.83 SLC7A5 (0.45) ALDH1A1TSHRTDP1KDM4EKMT2A
SCHEMBL19347435 0.79 SMN1; SMN2 (0.46) ALDH1A1TSHRL3MBTL1MAPK1KDM4E
SCHEMBL11105031 0.78 AKR1B1 (0.48) ALDH1A1TSHRKDM4EHTT
SCHEMBL456516 0.78 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Hydrochloric Acid SCHEMBL27576461 0.77 L3MBTL1 (0.58) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL27672935 0.77 ALDH1A1 (0.58) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL11113546 0.76 KEAP1 (0.52) ALDH1A1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL13291919 0.76 TSHR (0.51) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL27484985 0.75 ALDH1A1 (0.56) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL28915660 0.74 LTA4H (0.60) ALDH1A1TSHRTDP1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4443477-A ANTICOAGULANTS, ANTILIPEMIC AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1984-04-17 US disclosed