Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117475 | 0.84 | TSHR (0.67) | KEAP1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20981392 | 0.83 | KEAP1 (0.63) | KEAP1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL456516 | 0.80 | ALDH1A1 (0.59) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27576461 | 0.78 | L3MBTL1 (0.58) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL27672935 | 0.78 | ALDH1A1 (0.58) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL13291919 | 0.77 | TSHR (0.51) | TSHRALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL11105032 | 0.77 | KEAP1 (0.71) | KEAP1ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL27484985 | 0.77 | ALDH1A1 (0.56) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL11113544 | 0.76 | TLR7 (0.41) | TSHRALDH1A1SMN1; SMN2HTTCYP2D6 | |
| SCHEMBL28915660 | 0.76 | LTA4H (0.60) | TSHRALDH1A1SMN1; SMN2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443477-A | ANTICOAGULANTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-17 | — | — | US | disclosed |