Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830862 | 0.86 | KMT2A (0.55) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10511025 | 0.85 | KMT2A (0.72) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL13634694 | 0.84 | KMT2A (1.00) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL18619476 | 0.83 | POLB (0.58) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL4048976 | 0.74 | NPC1 (0.83) | KMT2AMEN1ALDH1A1MAPK1LMNA | |
| SCHEMBL11113900 | 0.73 | MAPK1 (0.78) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL10511793 | 0.73 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL20811963 | 0.71 | CRBN (0.74) | ALDH1A1LMNANPC1KDM4EHPGD | |
| SCHEMBL14839351 | 0.71 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL12083372 | 0.71 | KDM4E (0.73) | KMT2AMEN1ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140234365-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| EP-2750706-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | Alere San Diego, Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013049294-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013049294-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234365-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | SLC3A2, CTH, FABP1 | KMT2A 2015/4885MEN1 3017/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.