Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113438 | 0.82 | RAB9A (0.48) | RAB9ANPC1ALDH1A1MAPTTDP1 | |
| SCHEMBL11272029 | 0.73 | RAB9A (0.43) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL11271277 | 0.73 | RAB9A (0.43) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL8510873 | 0.69 | RAB9A (0.50) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| Phenylacetic Acid SCHEMBL11792837 | 0.68 | ALDH1A1 (0.57) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL6645015 | 0.68 | RAB9A (0.61) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL8716892 | 0.68 | RAB9A (0.61) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL6151831 | 0.68 | RAB9A (0.61) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL11595128 | 0.68 | RAB9A (0.46) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL6046672 | 0.67 | RAB9A (0.54) | RAB9ANPC1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031951-B1 | FORMYL DERIVATIVES OF HYDRAZINOMETHYLPENICILLINS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | CRAF Sud (IT) | 1984-07-25 | — | — | EP | disclosed |
| EP-0031951-A1 | Formyl derivatives of hydrazinomethylpenicillins, process for their preparation and pharmaceutical compositions containing these compounds | CRAF Sud (IT) | 1981-07-15 | — | — | EP | disclosed |