Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113040 | 0.86 | DRD2 (0.40) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL11109892 | 0.84 | KDM4E (0.40) | KMT2AMEN1ALDH1A1TP53MAPT | |
| SCHEMBL10274496 | 0.79 | SMN1; SMN2 (0.48) | KMT2AMEN1NPC1ALDH1A1TP53 | |
| SCHEMBL11112128 | 0.78 | ADRA2A (0.43) | KMT2AMEN1ALDH1A1TP53MAPT | |
| SCHEMBL11113990 | 0.78 | OPRM1 (0.47) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL1829260 | 0.76 | MAPT (0.58) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL27482179 | 0.74 | KDM4E (0.42) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL11114854 | 0.73 | MAPT (0.42) | NPC1ALDH1A1RAB9ATP53MAPT | |
| SCHEMBL5667100 | 0.73 | ALDH1A1 (0.49) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL19327260 | 0.72 | ADRA1A (0.49) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106988-A1 | Pharmacologically active lactam derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |