SCHEMBL111151

SCHEMBL111151

COc1ccc(Br)cc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
CYP3A4 P08684 2/20 0.59
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
KMT2A Q03164 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 1/20 0.56
GAA P10253 3/20 0.55
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
MGAM O43451 1/20 0.49
SI P14410 1/20 0.49
MGAM2 Q2M2H8 1/20 0.49
TDP1 Q9NUW8 3/20 0.48
APP P05067 2/20 0.48
ADRA2B P18089 1/20 0.48
PTGS1 P23219 1/20 0.48
TUBB4A P04350 2/20 0.46
TUBB P07437 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29689196 1.00 ALDH1A1 (0.59) ALDH1A1CYP3A4MEN1MAPTTHRB
Sulfuric Acid SCHEMBL28214565 0.89 CA1 (0.53) ALDH1A1CYP3A4MEN1MAPTTHRB
Maleic Acid SCHEMBL27604424 0.84 ALDH1A1 (0.51) ALDH1A1CYP3A4MEN1MAPTTHRB
SCHEMBL155113 0.82 ALDH1A1 (0.61) ALDH1A1CYP3A4MAPTL3MBTL1POLB
Hydrochloric Acid SCHEMBL28039298 0.80 ALDH1A1 (0.61) ALDH1A1CYP3A4MEN1MAPTTHRB
Bromide SCHEMBL7931348 0.80 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL205027 0.79 GAA (0.47) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL20509 0.78 CA2 (0.56) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL29419589 0.78 CA2 (0.56) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL359387 0.78 POLB (0.52) ALDH1A1CYP3A4MEN1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10179786-B2 Selective dual inhibitors of PI3 delta and gamma protein kinases RHIZEN PHARMACEUTICALS SA (CH) 2019-01-15 US claimed
EP-3160968-B1 SUBSTITUTED CHROMENE DERIVATIVES AS SELECTIVE DUAL INHIBITORS OF PI3 DELTA AND GAMMA PROTEIN KINASES RHIZEN PHARMACEUTICALS S A (CH) 2018-10-31 EP claimed
US-20170204106-A1 SELECTIVE DUAL INHIBITORS OF PI3 DELTA AND GAMMA PROTEIN KINASES RHIZEN PHARMACEUTICALS AG (CH) 2017-07-20 US claimed
US-20150376188-A1 SELECTIVE DUAL INHIBITORS OF PI3 DELTA AND GAMMA PROTEIN KINASES RHIZEN PHARMACEUTICALS AG (CH) 2015-12-31 US claimed
CN-102993022-A Preparation method of bromoaniline UNIV SHANGHAI ENG SCIENCE 2013-03-27 CN claimed
CN-102898369-A 3-amino-7-bromoquinoline-2-ethyl formate and preparation method thereof SHANGHAI SHUYA MEDICAL TECHNOLOGY CO LTD 2013-01-30 CN claimed
US-20260108527-A1 POLO LIKE KINASE 4 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2026-04-23 US disclosed
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
US-20260034140-A1 MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE REDX PHARMA LTD (GB) 2026-02-05 US disclosed
EP-3573972-B1 RORGAMMA MODULATORS AND USES THEREOF GENFIT (FR) 2026-01-14 EP disclosed
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
US-12453734-B2 Modulators of rho-associated protein kinase REDX PHARMA LIMITED (GB) 2025-10-28 US disclosed
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-0211272-A2 AZO compound and colored composition containing same DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1987-02-25 EP disclosed
US-4507237-A DISPERSE AND BASIC DYES HODOGAYA CHEMICAL CO., LTD. (JP) 1985-03-26 US disclosed
EP-0023770-A1 Cationic pyridone azo dyestuffs, certain novel coupling components from which they are derived and processes for the manufacture of the dyestuffs and the coupling components IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-02-11 EP disclosed
US-4169705-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-10-02 US disclosed
US-4160643-A FOR POLYMERS OF ACRYLONITRILE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-10 US disclosed
US-4153413-A DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-08 US disclosed
US-4134723-A DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204106-A1 SELECTIVE DUAL INHIBITORS OF PI3 DELTA AND GAMMA PROTEIN KINASES PIK3CD, PRKCZ, PRKCE ALDH1A1 4420/4885CYP3A4 4547/4885MEN1 4517/4885
US-20260108527-A1 POLO LIKE KINASE 4 INHIBITORS PLK4, PLK2, PLK3 ALDH1A1 2205/4885CYP3A4 1074/4885MEN1 4881/4885
US-20260034140-A1 MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE ROCK1, ROCK2, RHOA ALDH1A1 4825/4885CYP3A4 3853/4885MEN1 1566/4885
US-12453734-B2 Modulators of rho-associated protein kinase ROCK2, ROCK1, RHOA ALDH1A1 4441/4885CYP3A4 4539/4885MEN1 2942/4885
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 ALDH1A1 245/4885CYP3A4 434/4885MEN1 2679/4885
US-10179786-B2 Selective dual inhibitors of PI3 delta and gamma protein kinases PIK3CD, PRKCZ, PRKCE ALDH1A1 4420/4885CYP3A4 4547/4885MEN1 4517/4885
US-20150376188-A1 SELECTIVE DUAL INHIBITORS OF PI3 DELTA AND GAMMA PROTEIN KINASES PIK3CD, PRKCZ, PRKCE ALDH1A1 4415/4885CYP3A4 4523/4885MEN1 4495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.