Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116531 | 0.89 | MEN1 (0.54) | LMNAMEN1KMT2AROCK2MAPT | |
| SCHEMBL11114617 | 0.89 | KDR (0.48) | LMNAMEN1KMT2AROCK2MAPT | |
| SCHEMBL11119482 | 0.88 | ROCK2 (0.62) | ROCK2MAPTJAK2NTRK1RET | |
| SCHEMBL11116880 | 0.86 | LMNA (0.54) | LMNAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL11116691 | 0.85 | ALDH1A1 (0.45) | LMNAMEN1KMT2AROCK2MAPT | |
| SCHEMBL11116431 | 0.81 | SMN1; SMN2 (0.51) | LMNAMEN1KMT2AROCK2MAPT | |
| SCHEMBL11115815 | 0.81 | LMNA (0.50) | LMNAROCK2MAPTNPC1RAB9A | |
| SCHEMBL11123381 | 0.81 | KDR (0.51) | LMNAMEN1KMT2AROCK2MAPT | |
| SCHEMBL11117088 | 0.81 | PDGFRB (0.48) | LMNAMEN1KMT2AROCK2MAPT | |
| SCHEMBL11117644 | 0.80 | LMNA (0.59) | LMNAMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116853-A1 | Pyridazinones, processes for preparing them, therapeutical compositions containing these compounds and their use | BASF Aktiengesellschaft (DE) | 1984-08-29 | — | — | EP | disclosed |