Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10500739 | 0.73 | OPRM1 (0.33) | OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL11115862 | 0.70 | OPRM1 (0.37) | OPRM1SLC6A9 | |
| SCHEMBL11115639 | 0.69 | OPRM1 (0.41) | OPRM1ALDH1A1L3MBTL1OPRD1 | |
| SCHEMBL10499523 | 0.66 | KCNH2 (0.43) | OPRM1MAPTALDH1A1GAAPOLB | |
| SCHEMBL5695520 | 0.65 | OPRM1 (0.49) | OPRM1MAPTHPGDL3MBTL1OPRD1 | |
| SCHEMBL10501485 | 0.63 | ALDH1A1 (0.42) | OPRM1MAPTALDH1A1GAAPOLB | |
| SCHEMBL13592172 | 0.62 | PTBP1 (0.42) | PTBP1SLC6A9MAPTALDH1A1LMNA | |
| SCHEMBL11115855 | 0.62 | KDM4E (0.40) | OPRM1SLC6A9ALDH1A1GAAKDM4E | |
| SCHEMBL14433840 | 0.62 | KDM4E (0.41) | OPRM1KDM4E | |
| SCHEMBL14522110 | 0.62 | OPRM1 (0.50) | OPRM1LMNAKDM4EL3MBTL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |