Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118511 | 0.82 | MMP9 (0.41) | OPRM1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11117279 | 0.81 | OPRM1 (0.40) | OPRM1TSPOKMT2AMEN1TRPM8 | |
| SCHEMBL11117024 | 0.76 | DCUN1D1 (0.46) | OPRM1KMT2AMEN1PDK1ALDH1A1 | |
| SCHEMBL11119013 | 0.73 | MEN1 (0.38) | OPRM1KMT2AMEN1ALDH1A1OPRD1 | |
| SCHEMBL11115913 | 0.72 | SLC18A3 (0.45) | OPRM1L3MBTL1KCNH2 | |
| SCHEMBL11114003 | 0.71 | OPRM1 (0.37) | OPRM1KMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL11115641 | 0.69 | OPRM1 (0.37) | OPRM1L3MBTL1ALDH1A1OPRD1 | |
| SCHEMBL3563825 | 0.68 | OPRM1 (0.57) | OPRM1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16149920 | 0.68 | RAB9A (0.40) | TSPOKMT2AMEN1PDK1PDK2 | |
| SCHEMBL11115924 | 0.67 | OPRM1 (0.33) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |