Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ICMT | O60725 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167752 | 0.91 | MTNR1A (0.65) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL11114174 | 0.89 | MTNR1A (0.66) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL12520413 | 0.84 | MTNR1B (0.60) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL11115757 | 0.84 | MAPT (0.61) | MTNR1AMTNR1BMEN1KMT2AICMT | |
| SCHEMBL10126711 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL1493172 | 0.83 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL7505384 | 0.83 | MTNR1B (0.59) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL11117500 | 0.83 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL8557540 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL2090211 | 0.82 | MTNR1B (0.62) | MTNR1AMTNR1BMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | MTNR1A 79/4885MTNR1B 131/4885MEN1 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.