Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456478 | 0.77 | HTT (0.49) | DRD4GRIN2BHTR6PKMCYP1A2 | |
| SCHEMBL5878453 | 0.70 | PKM (0.57) | HTR6PKMNPC1GAA | |
| SCHEMBL3727998 | 0.70 | MGAM (0.41) | HTTNPC1GAANPSR1 | |
| SCHEMBL8817554 | 0.66 | PRNP (0.56) | GRIN2BGRIN1HTR6NPC1GAA | |
| SCHEMBL7474439 | 0.65 | HTR6 (0.48) | DRD4GRIN2BHTR6HTT | |
| SCHEMBL10872396 | 0.65 | MPO (0.44) | HTR6GAA | |
| SCHEMBL6885402 | 0.65 | ERCC1 (0.52) | — | |
| SCHEMBL7479562 | 0.64 | PARP1 (0.56) | GRIN2BHTR6 | |
| SCHEMBL10690713 | 0.64 | GAA (0.47) | GRIN2BGRIN1HTR6PKMCYP1A2 | |
| SCHEMBL9015054 | 0.63 | PRNP (0.46) | GRIN2BGRIN1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123962-A2 | Benzimidazole derivative, process for the preparation thereof and pharmaceutical composition | KANEBO, LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |