Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936848 | 0.81 | HTR1A (0.67) | SMN1; SMN2MAPTDRD4ALDH1A1HTR1A | |
| SCHEMBL8722756 | 0.80 | MAPT (0.72) | KDM4ESMN1; SMN2MAPTDRD4ALDH1A1 | |
| SCHEMBL11556531 | 0.79 | MAPK1 (0.69) | SMN1; SMN2MAPTDRD4ALDH1A1HTR1A | |
| SCHEMBL4005507 | 0.79 | DRD4 (1.00) | KDM4ESMN1; SMN2MAPTDRD4ALDH1A1 | |
| SCHEMBL14207957 | 0.78 | MAPT (0.66) | KDM4ESMN1; SMN2MAPTDRD4ALDH1A1 | |
| SCHEMBL18040093 | 0.78 | LMNA (0.78) | KDM4ESMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL4627292 | 0.78 | LMNA (0.67) | SMN1; SMN2MAPTALDH1A1TSHRHTT | |
| SCHEMBL5796341 | 0.77 | MAPT (0.65) | KDM4ESMN1; SMN2MAPTDRD4ALDH1A1 | |
| SCHEMBL29078413 | 0.77 | LMNA (0.60) | KDM4ESMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL4750163 | 0.77 | LMNA (1.00) | KDM4EMAPTALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120558-A1 | Antihypertensive N-piperazinylalkanoylanilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1984-10-03 | — | — | EP | disclosed |