Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002993 | 0.79 | CYP1A2 (0.34) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL7836565 | 0.73 | MMP1 (0.38) | FDPSCA12CA1CA2MMP1 | |
| SCHEMBL4995125 | 0.69 | MMP8 (0.40) | LMNAMMP8 | |
| SCHEMBL18486450 | 0.69 | MMP1 (0.43) | FDPSLMNAMMP1MMP2MMP8 | |
| SCHEMBL12570890 | 0.65 | LMNA (0.40) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL7185620 | 0.65 | LMNA (0.40) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL19211974 | 0.65 | LMNA (0.40) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL8718515 | 0.64 | MMP1 (0.33) | FDPSCA12CA1CA2MMP1 | |
| SCHEMBL10580976 | 0.63 | LMNA (0.45) | FDPSLMNACA2 | |
| SCHEMBL2087244 | 0.63 | LMNA (0.45) | FDPSLMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121117-A1 | Derivatives of dihydropyridine and production thereof | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-10-10 | — | — | EP | disclosed |