Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118056 | 0.79 | FDPS (0.33) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL7836565 | 0.73 | MMP1 (0.38) | FDPSCA12CA1CA2MMP1 | |
| SCHEMBL2978537 | 0.72 | LMNA (0.38) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL29136874 | 0.70 | PGK1 (0.33) | LMNA | |
| SCHEMBL18486450 | 0.69 | MMP1 (0.43) | FDPSLMNAMMP1MMP2MMP8 | |
| Phosphoric Acid SCHEMBL30928243 | 0.68 | ALDH1A1 (0.36) | CYP1A2CYP2D6FDPSLMNACA12 | |
| SCHEMBL9451028 | 0.67 | TP53 (0.35) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL282108 | 0.67 | TP53 (0.41) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL19211974 | 0.65 | LMNA (0.40) | FDPSLMNACA12CA1CA2 | |
| SCHEMBL12570890 | 0.65 | LMNA (0.40) | FDPSLMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284910-B1 | FARNESYL TRANSFERASE INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2001-09-04 | — | — | US | claimed |