Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228780 | 0.90 | CCKBR (0.39) | CCKBRCCKARHRH4ACESMN1; SMN2 | |
| SCHEMBL9226683 | 0.84 | LMNA (0.36) | CCKBRCCKARLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7439940 | 0.79 | ACE (0.59) | ACEMMEABCB11AGTR2PDE3A | |
| SCHEMBL7439947 | 0.79 | ACE (0.59) | ACEMMEABCB11AGTR2PDE3A | |
| SCHEMBL9230696 | 0.78 | CCKBR (0.39) | CCKBRCCKARLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11118972 | 0.76 | NFKB1 (0.46) | CCKBRCCKARLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9227099 | 0.74 | ACE (0.59) | ACEMME | |
| SCHEMBL8881603 | 0.73 | LMNA (0.49) | CCKBRCCKARLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10498972 | 0.73 | LMNA (0.49) | CCKBRCCKARLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9228102 | 0.71 | P2RX4 (0.40) | LMNAALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671172-A1 | AMINO ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |