Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207312 | 0.75 | TP53 (0.53) | ALDH1A1SLC6A3LMNATHRBMAPT | |
| SCHEMBL4053894 | 0.72 | DRD2 (0.54) | HTR1AADRA2ADRD1SLC6A4ADRA1A | |
| SCHEMBL16680290 | 0.71 | CYP1A2 (0.56) | ALDH1A1SLC6A3LMNATHRBMAPT | |
| SCHEMBL16680291 | 0.71 | CYP1A2 (0.56) | ALDH1A1SLC6A3LMNATHRBMAPT | |
| Hydrochloric Acid SCHEMBL20271390 | 0.71 | DRD2 (0.53) | HTR1AADRA2ADRD1SLC6A4ADRA1A | |
| SCHEMBL16679788 | 0.70 | CYP1A2 (0.54) | ALDH1A1SLC6A3LMNASMN1; SMN2THRB | |
| SCHEMBL16679790 | 0.70 | CYP1A2 (0.54) | ALDH1A1SLC6A3LMNASMN1; SMN2THRB | |
| Pipamperone SCHEMBL7405 | 0.70 | HTR1A (0.94) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL538546 | 0.69 | DRD3 (0.92) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| SCHEMBL11122002 | 0.67 | ALDH1A1 (0.71) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125046-A1 | Process for preparing pyrimidinetrione derivatives | SAPOS S.A. (CH) | 1984-11-14 | — | — | EP | disclosed |