Sugi Predict

Sugi Predict / Compounds / SCHEMBL2732048

SCHEMBL2732048

SCHEMBL2732048

O=C(O)c1ccccc1NS(=O)(=O)C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.60
▸ ALDH1A1 P00352 6/20 0.60
▸ MEN1 O00255 5/20 0.60
▸ GAA P10253 1/20 0.56
▸ CA2 P00918 1/20 0.54
▸ HSD17B10 Q99714 4/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ HPGD P15428 3/20 0.50
▸ POLB P06746 1/20 0.50
▸ CRHBP P24387 1/20 0.50
▸ CRHR2 Q13324 1/20 0.50
▸ TAS2R14 Q9NYV8 3/20 0.47
▸ FABP4 P15090 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ KCNK2 O95069 1/20 0.46
▸ KCNK10 P57789 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL810 0.98 KMT2A (0.58) KMT2AALDH1A1MEN1GAACA2
SCHEMBL6003301 0.85 FABP4 (0.49) KMT2AALDH1A1MEN1GAACA2
SCHEMBL3353838 0.85 CA2 (0.57) KMT2AALDH1A1MEN1CA2HSD17B10
SCHEMBL5444394 0.85 CA2 (0.53) KMT2AALDH1A1MEN1GAACA2
SCHEMBL594 0.85 CA2 (0.53) KMT2AALDH1A1MEN1GAACA2
SCHEMBL3526139 0.84 PDK1 (0.53) KMT2AALDH1A1MEN1GAACA2
SCHEMBL27575403 0.83 MEN1 (0.54) KMT2AALDH1A1MEN1CA2HSD17B10
SCHEMBL11123377 0.82 CA2 (0.50) KMT2AALDH1A1MEN1GAACA2
SCHEMBL31518457 0.82 TSHR (0.57) KMT2AALDH1A1MEN1GAACA2
SCHEMBL5892022 0.81 CA2 (0.46) KMT2AALDH1A1MEN1GAACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 — — US disclosed
WO-2025085848-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-04-24 — — WO disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 — — US disclosed
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2024-07-30 — — US disclosed
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 — — CN disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed
EP-3796975-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. (US) 2021-03-31 — — EP disclosed
CN-112204008-A Sulphonylaminobenzylamide and sulphonylaminobenzamide derivatives 吉利德科学公司 2021-01-08 — — CN disclosed
WO-2012061557-A2 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2012-05-10 — — WO disclosed
US-8084187-B2 Resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2011-12-27 — — US disclosed
US-20090253070-A1 RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-10-08 — — US disclosed
EP-1594847-A2 SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS Transtech Pharma, Inc. (US) 2005-11-16 — — EP disclosed
WO-2004071447-A9 SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS TRANSTECH PHARMA INC (US) 2005-10-13 — — WO disclosed
EP-1569646-A2 PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2005-09-07 — — EP disclosed
US-20050187277-A1 Substituted azole derivatives, compositions, and methods of use TRANSTECH PHARMA, INC. 2005-08-25 — — US disclosed
WO-2004071447-A2 SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS TRANSTECH PHARMA INC. (US) 2004-08-26 — — WO disclosed
WO-2004054974-A2 PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2004-07-01 — — WO disclosed
US-4288592-A Process for preparing amides by reaction in presence of molecular sieve AMERICAN CYANAMID COMPANY (US) 1981-09-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B KMT2A 1234/4885ALDH1A1 245/4885MEN1 1634/4885
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B KMT2A 1234/4885ALDH1A1 245/4885MEN1 1634/4885
US-20050187277-A1 Substituted azole derivatives, compositions, and methods of use PTPRO, PTPN5, PTPRE KMT2A 2145/4885ALDH1A1 747/4885MEN1 2851/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 KMT2A 2071/4885ALDH1A1 1507/4885MEN1 3346/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B KMT2A 1234/4885ALDH1A1 245/4885MEN1 1634/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B KMT2A 1234/4885ALDH1A1 245/4885MEN1 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.