Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732048 | 0.83 | KMT2A (0.60) | MEN1KMT2ALMNAKDM4EHPGD | |
| SCHEMBL11123377 | 0.82 | CA2 (0.50) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| Hydrochloric Acid SCHEMBL810 | 0.81 | KMT2A (0.58) | MEN1KMT2ALMNAKDM4EHPGD | |
| SCHEMBL5444394 | 0.81 | CA2 (0.53) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19221685 | 0.80 | HTT (0.72) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL11123655 | 0.79 | CA2 (0.51) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL6755857 | 0.79 | KMT2A (0.74) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL3353838 | 0.78 | CA2 (0.57) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL594 | 0.78 | CA2 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11123463 | 0.78 | ALDH1A1 (0.48) | KMT2ASMN1; SMN2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1358062-A | Macrophage scavenger receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-07-10 | — | — | CN | claimed |
| CN-1358062-A | Macrophage scavenger receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-07-10 | — | — | CN | disclosed |