SCHEMBL11123788

SCHEMBL11123788

CS(=O)(=O)N(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PER2 O15055 1/20 0.42
CRY1 Q16526 1/20 0.42
CRY2 Q49AN0 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
LMNA P02545 2/20 0.39
CNR2 P34972 1/20 0.39
HTR2C P28335 1/20 0.38
HTR6 P50406 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PTGS2 P35354 1/20 0.38
NR3C2 P08235 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5928513 0.85 AKR1C3 (0.47) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL1704542 0.82 PKM (0.50) HTTNPSR1HTR6PKMALDH1A1
SCHEMBL5928392 0.79 PLAU (0.48) HTTRAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL10954270 0.78 L3MBTL1 (0.40) L3MBTL1HTTNPSR1NPC1RAB9A
SCHEMBL28380035 0.78 NPSR1 (0.69) L3MBTL1HTTNPSR1NPC1RAB9A
SCHEMBL894882 0.73 TSHR (0.46) L3MBTL1NPC1RAB9APOLBMEN1
SCHEMBL5720785 0.72 ALDH1A1 (0.47) L3MBTL1LMNAALDH1A1POLBKMT2A
SCHEMBL844507 0.71 NPSR1 (0.45) L3MBTL1HTTNPSR1NPC1RAB9A
SCHEMBL29619639 0.71 NPSR1 (0.45) L3MBTL1HTTNPSR1NPC1RAB9A
SCHEMBL11498366 0.70 UGT2B7 (0.46) L3MBTL1HTTNPSR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0051366-B1 TWO-PART, ANAEROBICALLY-CURING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-18 EP disclosed
EP-0051366-A1 Two-part, anaerobically-curing compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-05-12 EP disclosed
US-4316000-A PERFLUOROALKYLSULFONANILIDE INITIATOR AND A TERTIARY OR SECONDARY AROMATIC AMINE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-16 US disclosed