SCHEMBL844507

SCHEMBL844507

CN(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP2A6 P11509 4/20 0.43
SIGMAR1 Q99720 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NR3C2 P08235 1/20 0.43
ITK Q08881 1/20 0.42
PDK2 Q15119 1/20 0.41
CYP1A2 P05177 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CHKA P35790 2/20 0.40
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
PDE5A O76074 1/20 0.40
S1PR4 O95977 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619639 1.00 NPSR1 (0.45) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL279628 0.94 CYP1A2 (0.42) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL22764497 0.94 CHKA (0.44) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL12048724 0.94 NR3C2 (0.42) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL5441435 0.93 HTT (0.49) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL14506081 0.92 ESR1 (0.46) NPSR1HTTL3MBTL1SIGMAR1ITK
SCHEMBL12047804 0.92 L3MBTL1 (0.41) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL279071 0.90 ALDH1A1 (0.42) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL13826719 0.90 ESR1 (0.42) NPSR1HTTL3MBTL1CYP2A6SIGMAR1
SCHEMBL12048712 0.90 ESR1 (0.42) NPSR1HTTL3MBTL1CYP2A6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986759-B1 USE OF A FLUORESCENT PROTEIN FOR DETECTING THE INTERACTION BETWEEN A MEMBRANE RECEPTOR AND ITS LIGAND CENTRE NAT RECH SCIENT (FR) 2006-04-26 EP claimed
WO-2004013178-A1 FUSION PROTEINS BETWEEN A FLUORESCENT PROTEIN AND AN IONOTROPIC RECEPTOR AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-02-12 WO claimed
EP-0986759-A2 USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2000-03-22 EP claimed
WO-1998055873-A2 USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1998-12-10 WO claimed
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-11858911-B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-11858911-B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-20230337531-A1 NOVEL COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2023-10-19 US disclosed
EP-4248997-A1 THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR COVID-19 Hiroshima University (JP) 2023-09-27 EP disclosed
US-20060194259-A1 Method for isolating an allosteric effector of a receptor UNIVERSITE LOUIS PASTEUR DE STRASSOURG (FR) 2006-08-31 US disclosed
EP-0986759-B1 USE OF A FLUORESCENT PROTEIN FOR DETECTING THE INTERACTION BETWEEN A MEMBRANE RECEPTOR AND ITS LIGAND CENTRE NAT RECH SCIENT (FR) 2006-04-26 EP disclosed
US-20050059036-A1 Use of a fluorescent protein for detecting interaction between a target protein and its ligand CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2005-03-17 US disclosed
EP-1514112-A2 METHOD FOR ISOLATING AN ALLOSTERIC EFFECTOR OF A RECEPTOR CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2005-03-16 EP disclosed
WO-2004013178-A1 FUSION PROTEINS BETWEEN A FLUORESCENT PROTEIN AND AN IONOTROPIC RECEPTOR AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-02-12 WO disclosed
WO-2003107004-A2 METHOD FOR ISOLATING AN ALLOSTERIC EFFECTOR OF A RECEPTOR CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2003-12-24 WO disclosed
US-5599911-A Fiber-reactive dyes having a central 1,3,5-triazine ring to which are bonded to a monoazo chromophore having another 1,3,5-triazine moiety and a second chromophore CIBA-GEIGY CORPORATION (US) 1997-02-04 US disclosed
WO-1996024580-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1996-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337531-A1 NOVEL COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CRY1, AHR, CRY2 NPSR1 2645/4885HTT 1078/4885L3MBTL1 707/4885
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device CCND1, CCND2, DRD1 NPSR1 2830/4885HTT 3449/4885L3MBTL1 294/4885
US-11858911-B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same CUTA, SQLE, HMGCR NPSR1 4166/4885HTT 3582/4885L3MBTL1 3737/4885
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 PIN1, ACE2, ACE NPSR1 2659/4885HTT 1580/4885L3MBTL1 1983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.