Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643709 | 0.82 | RHEB (0.41) | CYP3A4MRGPRX4TDP1INPPL1INPP5A | |
| SCHEMBL25220463 | 0.80 | TDP1 (0.37) | CYP3A4MAPK1FABP3MRGPRX4TDP1 | |
| SCHEMBL30023648 | 0.79 | INPPL1 (0.54) | CYP3A4MAPK1FABP3MRGPRX4INPPL1 | |
| SCHEMBL258268 | 0.79 | INPPL1 (0.54) | CYP3A4MAPK1FABP3MRGPRX4INPPL1 | |
| SCHEMBL11602041 | 0.76 | TDP1 (0.42) | CYP3A4MAPK1FABP3TDP1GPR84 | |
| SCHEMBL258267 | 0.74 | LMNA (0.36) | CYP3A4MAPK1FABP3MRGPRX4TDP1 | |
| SCHEMBL1641526 | 0.73 | TDP1 (0.57) | TDP1 | |
| SCHEMBL5822420 | 0.72 | LMNA (0.53) | MAPK1TDP1 | |
| SCHEMBL31661065 | 0.72 | LMNA (0.35) | CYP3A4MAPK1FABP3MRGPRX4TDP1 | |
| SCHEMBL28200093 | 0.72 | INPPL1 (0.33) | CYP3A4MAPK1FABP3MRGPRX4INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12224040-B2 | Movable type method applied to protein-ligand binding | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-02-11 | — | — | US | disclosed |
| US-10332616-B2 | Movable type method applied to protein-ligand binding | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2019-06-25 | — | — | US | disclosed |
| US-20160350474-A1 | MOVABLE TYPE METHOD APPLIED TO PROTEIN-LIGAND BINDING | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-01 | — | — | US | disclosed |
| US-9096615-B2 | Bridged bicyclic amino thiazine dioxide compounds as inhibitors of beta-secretase and methods of use thereof | AMGEN INC. (US) | 2015-08-04 | — | — | US | disclosed |
| CN-102311855-B | Aviation lubricating oil composition | OIL RES INST OF THE AIR FORCE PLA | 2013-04-24 | — | — | CN | disclosed |
| CN-102311855-A | Aviation lubricating oil composition | OIL RES INST OF THE AIR FORCE PLA | 2012-01-11 | — | — | CN | disclosed |
| EP-0013744-B1 | CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT | Standard Oil Company (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4233182-A | High activity catalyst for the polymerization of alpha-olefins | STANDARD OIL COMPANY (INDIANA) (US) | 1980-11-11 | — | — | US | disclosed |
| US-4233253-A | Method for the preparation of metal salts of phosphorus acid esters | STANDARD OIL COMPANY (INDIANA) (US) | 1980-11-11 | — | — | US | disclosed |
| EP-0013744-A1 | Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component | Standard Oil Company (US) | 1980-08-06 | — | — | EP | disclosed |