Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.30 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126358 | 0.80 | CYP3A4 (0.38) | TDP1FABP3MRGPRX4CYP3A4MAPK1 | |
| SCHEMBL3728711 | 0.75 | TDP1 (0.39) | TDP1L3MBTL1CYP3A4MAPK1MEN1 | |
| SCHEMBL11602041 | 0.73 | TDP1 (0.42) | TDP1L3MBTL1FABP3CYP3A4MAPK1 | |
| SCHEMBL258268 | 0.72 | INPPL1 (0.54) | FABP3MRGPRX4CYP3A4MAPK1LMNA | |
| SCHEMBL30023648 | 0.72 | INPPL1 (0.54) | FABP3MRGPRX4CYP3A4MAPK1LMNA | |
| SCHEMBL258267 | 0.67 | LMNA (0.36) | TDP1FABP3MRGPRX4CYP3A4MAPK1 | |
| SCHEMBL12300309 | 0.67 | L3MBTL1 (0.42) | L3MBTL1MRGPRX4MAPK1TSHRALDH1A1 | |
| SCHEMBL31661065 | 0.66 | LMNA (0.35) | TDP1FABP3MRGPRX4CYP3A4MAPK1 | |
| SCHEMBL11599512 | 0.66 | ALOX15 (0.34) | TDP1FABP3MRGPRX4CYP3A4MAPK1 | |
| SCHEMBL11022534 | 0.66 | ALOX15 (0.49) | TDP1L3MBTL1FABP3MRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |