SCHEMBL31661065

SCHEMBL31661065

O=P(Cl)(Oc1ccc(Cl)c(Cl)c1Cl)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
FABP3 P05413 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
INPPL1 O15357 1/20 0.31
AKT1 P31749 1/20 0.31
INPP5A Q14642 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258267 0.84 LMNA (0.36) LMNASMN1; SMN2CYP3A4MAPK1FABP3
SCHEMBL258268 0.81 INPPL1 (0.54) LMNASMN1; SMN2CYP3A4MAPK1FABP3
SCHEMBL30023648 0.81 INPPL1 (0.54) LMNASMN1; SMN2CYP3A4MAPK1FABP3
SCHEMBL3906733 0.81 SMN1; SMN2 (0.47) LMNASMN1; SMN2CYP3A4MAPK1MRGPRX4
SCHEMBL25269222 0.79 LMNA (0.33) LMNASMN1; SMN2CYP3A4MAPK1FABP3
SCHEMBL11599512 0.78 ALOX15 (0.34) LMNASMN1; SMN2CYP3A4MAPK1FABP3
SCHEMBL28200093 0.74 INPPL1 (0.33) LMNASMN1; SMN2CYP3A4MAPK1FABP3
SCHEMBL1368776 0.72 TDP1 (0.50) LMNASMN1; SMN2MAPK1TDP1
SCHEMBL11126358 0.72 CYP3A4 (0.38) CYP3A4MAPK1FABP3MRGPRX4TDP1
SCHEMBL10862683 0.71 MRGPRX4 (0.34) CYP3A4MAPK1FABP3MRGPRX4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151707-A1 METHOD FOR PREPARING MULTIMERS OF PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS ENTRADA THERAPEUTICS, INC. (US) 2025-07-17 WO disclosed