SCHEMBL30023648

SCHEMBL30023648

O=P(O)(O)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 12/20 0.54
INPP5A Q14642 6/20 0.54
AKT1 P31749 1/20 0.54
INPP5B P32019 2/20 0.48
SRC P12931 2/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
PDE3A Q14432 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
FABP3 P05413 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258268 1.00 INPPL1 (0.54) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL258267 0.83 LMNA (0.36) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL557291 0.82 INPPL1 (0.59) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL31661065 0.81 LMNA (0.35) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL28554379 0.80 INPPL1 (0.36) INPPL1INPP5AAKT1INPP5BCYP3A4
SCHEMBL28200093 0.80 INPPL1 (0.33) INPPL1INPP5AAKT1ALDH1A1CYP3A4
SCHEMBL11126358 0.79 CYP3A4 (0.38) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL25269222 0.78 LMNA (0.33) CYP3A4MAPK1FABP3MRGPRX4LMNA
SCHEMBL11599512 0.76 ALOX15 (0.34) KDM4EALDH1A1CYP3A4MAPK1FABP3
SCHEMBL10442736 0.76 INPPL1 (0.46) INPPL1INPP5AAKT1INPP5BSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115398342-A Film-forming composition 日产化学株式会社 2022-11-25 CN disclosed