SCHEMBL258268

SCHEMBL258268

O=P(O)(O)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 12/20 0.54
INPP5A Q14642 6/20 0.54
AKT1 P31749 1/20 0.54
INPP5B P32019 2/20 0.48
SRC P12931 2/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
PDE3A Q14432 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
FABP3 P05413 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023648 1.00 INPPL1 (0.54) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL258267 0.83 LMNA (0.36) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL557291 0.82 INPPL1 (0.59) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL31661065 0.81 LMNA (0.35) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL28554379 0.80 INPPL1 (0.36) INPPL1INPP5AAKT1INPP5BCYP3A4
SCHEMBL28200093 0.80 INPPL1 (0.33) INPPL1INPP5AAKT1ALDH1A1CYP3A4
SCHEMBL11126358 0.79 CYP3A4 (0.38) INPPL1INPP5AAKT1CYP3A4MAPK1
SCHEMBL25269222 0.78 LMNA (0.33) CYP3A4MAPK1FABP3MRGPRX4LMNA
SCHEMBL11599512 0.76 ALOX15 (0.34) KDM4EALDH1A1CYP3A4MAPK1FABP3
SCHEMBL10442736 0.76 INPPL1 (0.46) INPPL1INPP5AAKT1INPP5BSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
CN-101418117-B Aromatic polycarbonate resin composite TEIJIN CHEMICALS LTD 2013-06-26 CN claimed
US-7723276-B2 Oil for cutting and grinding by ultra low volume oil feed system and for sliding surface and method for cutting and grinding by ultra low volume feed system using the oil NIPPON OIL CORPORATION (JP) 2010-05-25 US claimed
JP-11279398-A None JP disclosed
US-20260092167-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2026-04-02 US disclosed
US-20260008920-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2026-01-08 US disclosed
EP-4667531-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Limited (JP) 2025-12-24 EP disclosed
US-12441922-B2 Refrigerant-containing composition, use of same, refrigerator having same, operation method for said refrigerator, and refrigeration cycle device equipped with same DAIKIN INDUSTRIES, LTD. (JP) 2025-10-14 US disclosed
EP-4592353-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Limited (JP) 2025-07-30 EP disclosed
EP-4585644-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE FORMED OF SAME Teijin Limited (JP) 2025-07-16 EP disclosed
CN-120082186-A Resin composition 帝人株式会社 2025-06-03 CN disclosed
EP-0435253-A1 Refrigerator oils for use with hydrogen-containing halogenocarbon refrigerants NIPPON OIL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed
EP-0422797-A1 Fire retardant compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-17 EP disclosed
EP-0384724-A1 A method for lubricating refrigerating machines NIPPON OIL CO. LTD. (JP) 1990-08-29 EP disclosed
US-4818673-A BLEACH, FIXING SOLUTION CONTAINING FERRIC COMPLEX FUJI PHOTO FILM CO., LTD. (JP) 1989-04-04 US disclosed
EP-0013744-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT Standard Oil Company (US) 1984-11-07 EP disclosed
US-4233182-A High activity catalyst for the polymerization of alpha-olefins STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
US-4233253-A Method for the preparation of metal salts of phosphorus acid esters STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
EP-0013744-A1 Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component Standard Oil Company (US) 1980-08-06 EP disclosed
US-3954823-A Interconversion of stereoisomeric cycloorganosiloxanes DOW CORNING CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008920-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF NOP2, CCT2, RPL8 INPPL1 1955/4885INPP5A 4452/4885AKT1 3489/4885
US-20260092167-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF PAH, SEM1, ASH2L INPPL1 586/4885INPP5A 750/4885AKT1 3588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.