Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732134 | 1.00 | SLC6A3 (0.35) | SLC6A3MAPTGAALMNATSHR | |
| SCHEMBL10900941 | 0.80 | LMNA (0.35) | MAPTGAALMNATSHRMAOB | |
| SCHEMBL12116218 | 0.75 | CNR1 (0.35) | SLC6A3MAPTGAALMNAPDE4A | |
| SCHEMBL10238221 | 0.74 | — | — | |
| SCHEMBL17376700 | 0.74 | NR3C1 (0.32) | MAPTLMNATSHRMAPK1 | |
| SCHEMBL17376701 | 0.74 | NR3C1 (0.32) | MAPTLMNATSHRMAPK1 | |
| SCHEMBL18971261 | 0.73 | SLC6A3 (0.37) | SLC6A3MAPTMAPK1HPGD | |
| SCHEMBL12116226 | 0.73 | SLC6A3 (0.37) | SLC6A3MAPTMAPK1HPGD | |
| SCHEMBL15821591 | 0.73 | SLC6A3 (0.35) | SLC6A3TSHR | |
| SCHEMBL13220572 | 0.70 | SLC6A3 (0.41) | SLC6A3MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4422870-A | MITICIDE, MITE OVICIDE, HERBICIDE | UNION CARBIDE CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |