Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12116226 | 1.00 | SLC6A3 (0.37) | SLC6A3ACACBACACAKDM4EALDH1A1 | |
| SCHEMBL12116234 | 0.84 | SLC6A3 (0.41) | SLC6A3MAPT | |
| SCHEMBL13220572 | 0.84 | SLC6A3 (0.41) | SLC6A3MAPT | |
| SCHEMBL13220573 | 0.82 | CYP11B2 (0.35) | SLC6A3CYP11B1CYP11B2 | |
| SCHEMBL12116248 | 0.82 | CYP11B2 (0.35) | SLC6A3CYP11B1CYP11B2 | |
| SCHEMBL18971237 | 0.82 | HSD17B1 (0.36) | SLC6A3ACACBACACAMAPTHPGD | |
| SCHEMBL18971735 | 0.82 | HSD17B1 (0.36) | SLC6A3ACACBACACAMAPTHPGD | |
| SCHEMBL12115786 | 0.82 | HSD17B1 (0.36) | SLC6A3ACACBACACAMAPTHPGD | |
| SCHEMBL15099679 | 0.80 | SLC6A3 (0.34) | SLC6A3HSD17B1TDP2 | |
| SCHEMBL13042259 | 0.76 | DGAT1 (0.34) | SLC6A3ACACBACACADGAT1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155645-B1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LTD (GB) | 2017-06-14 | — | — | EP | disclosed |