Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933506 | 0.88 | KDM4E (0.36) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL30387993 | 0.87 | KDM4E (0.34) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL5176527 | 0.85 | KDM4E (0.41) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL15058572 | 0.84 | ALDH1A1 (0.38) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL5158783 | 0.81 | KDM4E (0.39) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL6261612 | 0.81 | TP53 (0.39) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL11822323 | 0.80 | MAPT (0.58) | KDM4EGAAMAPK1KMT2AMEN1 | |
| SCHEMBL108260 | 0.79 | ALDH1A1 (0.42) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL5692217 | 0.78 | KDM4E (0.54) | KDM4EGLAGAAMAPK1KMT2A | |
| SCHEMBL454595 | 0.76 | TNF (0.44) | KDM4EGLAGAAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-12-31 | — | — | US | claimed |
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-08 | — | — | US | claimed |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-01 | — | — | US | claimed |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-09-24 | — | — | US | claimed |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | claimed |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-10-05 | — | — | US | claimed |
| US-20230270649-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | claimed |
| WO-2023163907-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | claimed |
| WO-2023163908-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| EP-1726289-A2 | Dyeing composition for keratin fibres which contains a reducing agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-29 | — | — | EP | claimed |
| WO-2006108505-A2 | OXIDATION DYES COMPRISING 2-FURANONES AND COLLAGEN (DERIVATIVES) | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-10-19 | — | — | WO | claimed |
| EP-1707242-A1 | Oxidative hair colouring composition comprising 1,5- and /or 2,7-dihydroxy naphthalene and at least one further coupling agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-10-04 | — | — | EP | claimed |
| WO-2006048069-A1 | OXIDATION DYE WITHOUT A DEVELOPER COMPONENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-05-11 | — | — | WO | claimed |
| EP-1647266-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-04-19 | — | — | EP | claimed |
| WO-2006018089-A1 | OXIDATION COLORANTS COMPRISING DIAMINOBENZENE DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-02-23 | — | — | WO | claimed |
| US-20060016024-A1 | Novel coupling components | PARALLEL WIRELESS, INC. | 2006-01-26 | — | — | US | claimed |
| EP-1583511-B1 | NOVEL COUPLING COMPONENTS | HENKEL KGAA (DE) | 2005-11-09 | — | — | EP | claimed |
| EP-1583511-A1 | NOVEL COUPLING COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-12 | — | — | EP | claimed |
| WO-2004058205-A1 | NOVEL COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | KDM4E 1626/4885GLA 1350/4885GAA 4422/4885 |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | KDM4E 1573/4885GLA 1195/4885GAA 4289/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | KDM4E 1526/4885GLA 95/4885GAA 2405/4885 |
| US-20230270649-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | KDM4E 1126/4885GLA 915/4885GAA 4387/4885 |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | KDM4E 1445/4885GLA 639/4885GAA 3966/4885 |
| US-20060016024-A1 | Novel coupling components | KRT18, H1-4, H1-3 | KDM4E 1269/4885GLA 2367/4885GAA 4879/4885 |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | KDM4E 1573/4885GLA 1195/4885GAA 4289/4885 |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, ALDH2 | KDM4E 1626/4885GLA 1350/4885GAA 4422/4885 |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | KDM4E 1126/4885GLA 915/4885GAA 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.