Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144373 | 0.92 | KMT2A (0.61) | MAPTMAPK1NPC1KMT2AMEN1 | |
| SCHEMBL11136396 | 0.85 | SMN1; SMN2 (0.61) | MAPTMAPK1NPC1RAB9AKMT2A | |
| SCHEMBL11139020 | 0.81 | CSNK2A1 (0.66) | MAPTMAPK1CSNK2A1NPC1RAB9A | |
| SCHEMBL11142941 | 0.79 | RAB9A (0.57) | MAPTMAPK1NPC1RAB9AKMT2A | |
| SCHEMBL11120333 | 0.77 | PARP1 (0.59) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10519110 | 0.77 | ALDH1A1 (0.42) | MAPTMAPK1NPC1RAB9AKMT2A | |
| SCHEMBL12302712 | 0.77 | MEN1 (0.67) | MAPTMAPK1CSNK2A1NPC1RAB9A | |
| SCHEMBL24263371 | 0.76 | NPC1 (0.65) | MAPTMAPK1CSNK2A1NPC1RAB9A | |
| SCHEMBL11141222 | 0.76 | LMNA (0.46) | MAPTMAPK1NPC1RAB9AKMT2A | |
| SCHEMBL1821135 | 0.75 | KMT2A (0.69) | MAPTMAPK1CSNK2A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |