Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051530 | 0.89 | GAA (0.50) | ALDH1A1POLBGAALMNAALOX12 | |
| SCHEMBL11083418 | 0.89 | L3MBTL1 (0.46) | ALDH1A1POLBGAALMNAL3MBTL1 | |
| SCHEMBL11665157 | 0.84 | DRD2 (0.40) | ALDH1A1POLBGAACYP1A2CYP2C9 | |
| SCHEMBL11138222 | 0.82 | GAA (0.44) | ALDH1A1POLBGAALMNAALOX12 | |
| SCHEMBL7168279 | 0.82 | DRD2 (0.55) | ALDH1A1POLBLMNACYP1A2CYP2C9 | |
| SCHEMBL11136337 | 0.82 | GAA (0.68) | ALDH1A1POLBGAALMNAALOX12 | |
| SCHEMBL11135124 | 0.82 | LMNA (0.48) | ALDH1A1POLBGAALMNAALOX12 | |
| SCHEMBL11137877 | 0.81 | HTT (0.43) | ALDH1A1GAAALOX12L3MBTL1MAPT | |
| SCHEMBL11142783 | 0.79 | ATM (0.45) | ALDH1A1POLBGAALMNAALOX12 | |
| SCHEMBL11054653 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBGAALMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |